| Found in Collection(s): | Click on the collection logo for more information.
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| Collection Name: | Directory of Open Access Journals: Biology and Life Sciences
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| Collection Description: | The Directory of Open Access Journals (DOAJ): Biology and Life Sciences indexes open-access journals devoted to anatomy, biochemistry, biotechnology, botany, cytology, genetics, microbiology, physiology, and zoology. DOAJ aims to increase the visibility and ease of use of all open-access scientific and scholarly journals that use a quality-control system, worldwide and in all languages. |
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Collection Information:
| Grade Level |
Higher Education
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| Intended Audience |
Educator
Professional/Practitioner
Researcher
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| Language |
Croatian
Turkish
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| Link |
Http://www.doaj.org/ljbs?cpid=67
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| Publisher / Resource Provider |
Lund University Libraries Head Office
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| Resource Type |
Article
Collection
Periodical
Reference Material
Text
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| Subject Keyword(s) |
Life Sciences
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| Resource Title: | Effect of Short Time Morphine Addiction on the Kidney Tissue in Rat
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| Description: | Opium is an important substance that abuses and has very pharmacological and pathological effects. Morphine is the main substance of opium. In the recent study, it has been tried to identify the short effects of morphine on the kidney pathology of Rats. The randomized double blind study was designed. Twenty rats were selected and divided in two groups and maintained under routine laboratory conditions and similar intervention. One group had been addicted orally by morphine powder and control were not addict. After three weeks, all rats were anesthetized and underwent autopsy. Their kidneys were removed en-block and sent to pathology laboratory and reviewed by one pathologist. The major considered variables were tubulo-interstitial and glomerular changes, glomerular amount and size on light microscope view. Glomerular, tubular and vascular changes, glomerular counts, glomerular size, and cortical thickness showed no significant differences between groups of study. Only Lymphocytic infiltration was higher frequency in addict group, significantly P=0.007. It seems short course of morphine consumption is very little effect on kidney, only Lymphocytic infiltration observe in addicted renal tissue which, may be precursor of other changes in kidney. It is better long term studies are implemented in this course. |
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Additional Resource Information
| Author |
Reza Malekpourafshar and Hamid Zeinalinejad
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| Date Published |
2005
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| Publisher / Resource Provider |
Science Publications
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| Subject Keyword(s) |
Addict
Kidney
Morphine
Rat
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